Xanthurenic acid

Xanthurenic acid

Chembox new
Reference="Merck Index", 11th Edition, 9977.]
ImageFile=Xanthurenic acid.pngImageSize=150px
IUPACName=8-Hydroxy-4-oxo-1"H"-quinoline-2-carboxylic acid
OtherNames=Xanthuric acid
Xanthurenate
8-Hydroxykynurenic acid
4,8-Dihydroxyquinaldic acid
Section1= Chembox Identifiers
CASNo=59-00-7
PubChem=5699
SMILES=OC2=CC(C(O)=O)=NC1=C(O)C=CC=C12

Section2= Chembox Properties
Formula=C10H7NO4
MolarMass=205.17 g/mol
Appearance=Yellow crystals
Density=
MeltingPtC=286
BoilingPt=
Solubility=Insoluble

Section3= Chembox Hazards
MainHazards=
FlashPt=
Autoignition=

Xanthurenic acid is a chemical shown to induce gametogenesis of "Plasmodium falciparum", the parasite that causes malaria.cite journal
last = Billker
first =
authorlink =
coauthors =
title = Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito
journal = Nature
volume = 392
issue =
pages = 289–292
publisher =
location =
date = March 19, 1998
doi =
id =
accessdate =
] It is found in the gut of the "Anopheles" mosquito.

Xanthurenic acid is a metabolic intermediate that accumulates and is excreted by pyridoxine (vitamin B6) deficient animals after the ingestion of tryptophan. [ [http://www.sigmaaldrich.com/catalog/search/ProductDetail/FLUKA/95570 Xanthurenic acid] at Sigma-Aldrich]

ee also

* Kynurenic acid

References


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  • xanthurenic acid — The sulfur yellow crystals form a red compound with Millon reagent, or an intensely green one with ferrous sulfate; excreted in the urine of pyridoxine deficient animals after the ingestion of tryptophan, and of rats fed almost exclusively with… …   Medical dictionary

  • xanthurenic acid — |zan(t)th(y)ə|renik noun Etymology: xanth + urenic (as in kynurenic) : a yellow crystalline phenolic acid (HO)2C9H4NCOOH closely related to kynurenic acid and excreted in the urine when tryptophan is added to the diet of experimental animals… …   Useful english dictionary

  • Kynurenic acid — Chembox new Name = Kynurenic acid ImageFile = KynurenicAcid.png ImageName = Chemical structure of kynurenic acid IUPACName = 4 oxo 1H quinoline 2 carboxylic acid OtherNames = Kinurenic acid, kynuronic acid, quinurenic acid, transtorine Section1 …   Wikipedia

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  • Vitamin B6 — is a water soluble vitamin. Pyridoxal phosphate (PLP) is the active form and is a cofactor in many reactions of amino acid metabolism, including transamination, deamination, and decarboxylation. PLP also is necessary for the enzymatic reaction… …   Wikipedia

  • tryptophan load test — (for vitamin B6 deficiency) a single large dose of tryptophan is administered orally and a 24 hour urine sample is analyzed for xanthurenic acid, and sometimes also kynurenine, hydroxykynurenine, and kynurenic acid. If vitamin B6 deficiency… …   Medical dictionary

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  • hydroxykynureninuria — An abnormality in tryptophan metabolism, probably due to a defect in kynureninase, characterized by mild mental retardation, migraine like headaches, and urinary excretion of large amounts of kynurenine, 3 hydoxykynurenine, and xanthurenic acid …   Medical dictionary

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