- TSPAN31
Tetraspanin 31, also known as TSPAN31, is a human
gene .cite web | title = Entrez Gene: TSPAN31 tetraspanin 31| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6302| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.cite web | title = Entrez Gene: TSPAN31 tetraspanin 31| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6302| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Wright MD, Tomlinson MG |title=The ins and outs of the transmembrane 4 superfamily. |journal=Immunol. Today |volume=15 |issue= 12 |pages= 588–94 |year= 1995 |pmid= 7531445 |doi=
*cite journal | author=Meltzer PS, Jankowski SA, Dal Cin P, "et al." |title=Identification and cloning of a novel amplified DNA sequence in human malignant fibrous histiocytoma derived from a region of chromosome 12 frequently rearranged in soft tissue tumors. |journal=Cell Growth Differ. |volume=2 |issue= 10 |pages= 495–501 |year= 1992 |pmid= 1661131 |doi=
*cite journal | author=Jankowski SA, De Jong P, Meltzer PS |title=Genomic structure of SAS, a member of the transmembrane 4 superfamily amplified in human sarcomas. |journal=Genomics |volume=25 |issue= 2 |pages= 501–6 |year= 1995 |pmid= 7789984 |doi=
*cite journal | author=Jankowski SA, Mitchell DS, Smith SH, "et al." |title=SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins. |journal=Oncogene |volume=9 |issue= 4 |pages= 1205–11 |year= 1994 |pmid= 8134123 |doi=
*cite journal | author=Elkahloun AG, Krizman DB, Wang Z, "et al." |title=Transcript mapping in a 46-kb sequenced region at the core of 12q13.3 amplification in human cancers. |journal=Genomics |volume=42 |issue= 2 |pages= 295–301 |year= 1997 |pmid= 9192850 |doi= 10.1006/geno.1997.4727
*cite journal | author=Wunder JS, Eppert K, Burrow SR, "et al." |title=Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas. |journal=Oncogene |volume=18 |issue= 3 |pages= 783–8 |year= 1999 |pmid= 9989829 |doi= 10.1038/sj.onc.1202346
*cite journal | author=Ragazzini P, Gamberi G, Benassi MS, "et al." |title=Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma. |journal=Cancer Detect. Prev. |volume=23 |issue= 2 |pages= 129–36 |year= 1999 |pmid= 10101594 |doi=
*cite journal | author=Suzuki Y, Tsunoda T, Sese J, "et al." |title=Identification and characterization of the potential promoter regions of 1031 kinds of human genes. |journal=Genome Res. |volume=11 |issue= 5 |pages= 677–84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr.164001
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Ragazzini P, Gamberi G, Pazzaglia L, "et al." |title=Amplification of CDK4, MDM2, SAS and GLI genes in leiomyosarcoma, alveolar and embryonal rhabdomyosarcoma. |journal=Histol. Histopathol. |volume=19 |issue= 2 |pages= 401–11 |year= 2004 |pmid= 15024701 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
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