GUCY1B3

Guanylate cyclase 1, soluble, beta 3, also known as GUCY1B3, is a human gene.cite web | title = Entrez Gene: GUCY1B3 guanylate cyclase 1, soluble, beta 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2983| accessdate = ]

PBB_Summary
section_title =
summary_text = Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998). [supplied by OMIM] cite web | title = Entrez Gene: GUCY1B3 guanylate cyclase 1, soluble, beta 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2983| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lucas KA, Pitari GM, Kazerounian S, "et al." |title=Guanylyl cyclases and signaling by cyclic GMP. |journal=Pharmacol. Rev. |volume=52 |issue= 3 |pages= 375–414 |year= 2000 |pmid= 10977868 |doi=
*cite journal | author=Giuili G, Scholl U, Bulle F, Guellaën G |title=Molecular cloning of the cDNAs coding for the two subunits of soluble guanylyl cyclase from human brain. |journal=FEBS Lett. |volume=304 |issue= 1 |pages= 83–8 |year= 1992 |pmid= 1352257 |doi=
*cite journal | author=Chhajlani V, Frändberg PA, Ahlner J, "et al." |title=Heterogeneity in human soluble guanylate cyclase due to alternative splicing. |journal=FEBS Lett. |volume=290 |issue= 1-2 |pages= 157–8 |year= 1991 |pmid= 1680753 |doi=
*cite journal | author=Giuili G, Roechel N, Scholl U, "et al." |title=Colocalization of the genes coding for the alpha 3 and beta 3 subunits of soluble guanylyl cyclase to human chromosome 4 at q31.3-q33. |journal=Hum. Genet. |volume=91 |issue= 3 |pages= 257–60 |year= 1993 |pmid= 8097486 |doi=
*cite journal | author=Papapetropoulos A, Cziraki A, Rubin JW, "et al." |title=cGMP accumulation and gene expression of soluble guanylate cyclase in human vascular tissue. |journal=J. Cell. Physiol. |volume=167 |issue= 2 |pages= 213–21 |year= 1996 |pmid= 8613461 |doi= 10.1002/(SICI)1097-4652(199605)167:2<213::AID-JCP4>3.0.CO;2-S |doilabel=10.1002/(SICI)1097-4652(199605)167:2213::AID-JCP43.0.CO;2-S
*cite journal | author=Zabel U, Weeger M, La M, Schmidt HH |title=Human soluble guanylate cyclase: functional expression and revised isoenzyme family. |journal=Biochem. J. |volume=335 ( Pt 1) |issue= |pages= 51–7 |year= 1998 |pmid= 9742212 |doi=
*cite journal | author=Russwurm M, Wittau N, Koesling D |title=Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes. |journal=J. Biol. Chem. |volume=276 |issue= 48 |pages= 44647–52 |year= 2002 |pmid= 11572861 |doi= 10.1074/jbc.M105587200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Venema RC, Venema VJ, Ju H, "et al." |title=Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase. |journal=Am. J. Physiol. Heart Circ. Physiol. |volume=285 |issue= 2 |pages= H669–78 |year= 2003 |pmid= 12676772 |doi= 10.1152/ajpheart.01025.2002
*cite journal | author=Meurer S, Pioch S, Wagner K, "et al." |title=AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase. |journal=J. Biol. Chem. |volume=279 |issue= 47 |pages= 49346–54 |year= 2005 |pmid= 15381706 |doi= 10.1074/jbc.M410565200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Mateos-Cáceres PJ, Garcia-Cardoso J, Lapuente L, "et al." |title=Soluble guanylate cyclase beta1-subunit expression is increased in mononuclear cells from patients with erectile dysfunction. |journal=Int. J. Impot. Res. |volume=18 |issue= 5 |pages= 432–7 |year= 2006 |pmid= 16528291 |doi= 10.1038/sj.ijir.3901461

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