ANGPT4

Angiopoietin 4, also known as ANGPT4, is a human gene.cite web | title = Entrez Gene: ANGPT4 angiopoietin 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51378| accessdate = ]

PBB_Summary
section_title =
summary_text = Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin.cite web | title = Entrez Gene: ANGPT4 angiopoietin 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51378| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Valenzuela DM, Griffiths JA, Rojas J, "et al." |title=Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 5 |pages= 1904–9 |year= 1999 |pmid= 10051567 |doi=
*cite journal | author=Nishimura M, Miki T, Yashima R, "et al." |title=Angiopoietin-3, a novel member of the angiopoietin family. |journal=FEBS Lett. |volume=448 |issue= 2-3 |pages= 254–6 |year= 1999 |pmid= 10218486 |doi=
*cite journal | author=Grosios K, Leek JP, Markham AF, "et al." |title=Assignment of ANGPT4, ANGPT1, and ANGPT2 encoding angiopoietins 4, 1 and 2 to human chromosome bands 20p13, 8q22.3-->q23 and 8p23.1, respectively, by in situ hybridization and radiation hybrid mapping. |journal=Cytogenet. Cell Genet. |volume=84 |issue= 1-2 |pages= 118–20 |year= 1999 |pmid= 10343124 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Ward EG, Grosios K, Markham AF, Jones PF |title=Genomic structures of the human angiopoietins show polymorphism in angiopoietin-2. |journal=Cytogenet. Cell Genet. |volume=94 |issue= 3-4 |pages= 147–54 |year= 2002 |pmid= 11856872 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zeng L, Dai J, Ying K, "et al." |title=Identification of a novel human angiopoietin-like gene expressed mainly in heart. |journal=J. Hum. Genet. |volume=48 |issue= 3 |pages= 159–62 |year= 2003 |pmid= 12624729 |doi= 10.1007/s100380300025
*cite journal | author=Yamakawa M, Liu LX, Belanger AJ, "et al." |title=Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis. |journal=Am. J. Physiol. Renal Physiol. |volume=287 |issue= 4 |pages= F649–57 |year= 2004 |pmid= 15198927 |doi= 10.1152/ajprenal.00028.2004
*cite journal | author=Lee HJ, Cho CH, Hwang SJ, "et al." |title=Biological characterization of angiopoietin-3 and angiopoietin-4. |journal=FASEB J. |volume=18 |issue= 11 |pages= 1200–8 |year= 2005 |pmid= 15284220 |doi= 10.1096/fj.03-1466com
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Oliner J, Min H, Leal J, "et al." |title=Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2. |journal=Cancer Cell |volume=6 |issue= 5 |pages= 507–16 |year= 2004 |pmid= 15542434 |doi= 10.1016/j.ccr.2004.09.030
*cite journal | author=Olsen MW, Ley CD, Junker N, "et al." |title=Angiopoietin-4 inhibits angiogenesis and reduces interstitial fluid pressure. |journal=Neoplasia |volume=8 |issue= 5 |pages= 364–72 |year= 2006 |pmid= 16790085 |doi= 10.1593/neo.06127

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