QSOX1

QSOX1

Quiescin Q6, also known as QSCN6, is a human gene.cite web | title = Entrez Gene: QSCN6 quiescin Q6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5768| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.cite web | title = Entrez Gene: QSCN6 quiescin Q6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5768| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Thorpe C, Hoober KL, Raje S, "et al." |title=Sulfhydryl oxidases: emerging catalysts of protein disulfide bond formation in eukaryotes. |journal=Arch. Biochem. Biophys. |volume=405 |issue= 1 |pages= 1–12 |year= 2002 |pmid= 12176051 |doi=
*cite journal | author=Coppock DL, Kopman C, Scandalis S, Gilleran S |title=Preferential gene expression in quiescent human lung fibroblasts. |journal=Cell Growth Differ. |volume=4 |issue= 6 |pages= 483–93 |year= 1993 |pmid= 8396966 |doi=
*cite journal | author=Coppock DL, Cina-Poppe D, Gilleran S |title=The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1. |journal=Genomics |volume=54 |issue= 3 |pages= 460–8 |year= 1999 |pmid= 9878249 |doi= 10.1006/geno.1998.5605
*cite journal | author=Hoober KL, Glynn NM, Burnside J, "et al." |title=Homology between egg white sulfhydryl oxidase and quiescin Q6 defines a new class of flavin-linked sulfhydryl oxidases. |journal=J. Biol. Chem. |volume=274 |issue= 45 |pages= 31759–62 |year= 1999 |pmid= 10542195 |doi=
*cite journal | author=Coppock D, Kopman C, Gudas J, Cina-Poppe DA |title=Regulation of the quiescence-induced genes: quiescin Q6, decorin, and ribosomal protein S29. |journal=Biochem. Biophys. Res. Commun. |volume=269 |issue= 2 |pages= 604–10 |year= 2000 |pmid= 10708601 |doi= 10.1006/bbrc.2000.2324
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
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*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Radom J, Colin D, Thiebault F, "et al." |title=Identification and expression of a new splicing variant of FAD-sulfhydryl oxidase in adult rat brain. |journal=Biochim. Biophys. Acta |volume=1759 |issue= 5 |pages= 225–33 |year= 2006 |pmid= 16806532 |doi= 10.1016/j.bbaexp.2006.04.008
*cite journal | author=Chakravarthi S, Jessop CE, Willer M, "et al." |title=Intracellular catalysis of disulfide bond formation by the human sulfhydryl oxidase, QSOX1. |journal=Biochem. J. |volume=404 |issue= 3 |pages= 403–11 |year= 2007 |pmid= 17331072 |doi= 10.1042/BJ20061510
*cite journal | author=Jaje J, Wolcott HN, Fadugba O, "et al." |title=A flavin-dependent sulfhydryl oxidase in bovine milk. |journal=Biochemistry |volume=46 |issue= 45 |pages= 13031–40 |year= |pmid= 17944490 |doi= 10.1021/bi7016975

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