MAGI2

Membrane associated guanylate kinase, WW and PDZ domain containing 2, also known as MAGI2, is a human gene.cite web | title = Entrez Gene: MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9863| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family.cite web | title = Entrez Gene: MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9863| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wood JD, Yuan J, Margolis RL, "et al." |title=Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins. |journal=Mol. Cell. Neurosci. |volume=11 |issue= 3 |pages= 149–60 |year= 1998 |pmid= 9647693 |doi= 10.1006/mcne.1998.0677
*cite journal | author=Ishikawa K, Nagase T, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 3 |pages= 169–76 |year= 1998 |pmid= 9734811 |doi=
*cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=
*cite journal | author=Ide N, Hata Y, Deguchi M, "et al." |title=Interaction of S-SCAM with neural plakophilin-related Armadillo-repeat protein/delta-catenin. |journal=Biochem. Biophys. Res. Commun. |volume=256 |issue= 3 |pages= 456–61 |year= 1999 |pmid= 10080919 |doi= 10.1006/bbrc.1999.0364
*cite journal | author=Shoji H, Tsuchida K, Kishi H, "et al." |title=Identification and characterization of a PDZ protein that interacts with activin type II receptors. |journal=J. Biol. Chem. |volume=275 |issue= 8 |pages= 5485–92 |year= 2000 |pmid= 10681527 |doi=
*cite journal | author=Wu X, Hepner K, Castelino-Prabhu S, "et al." |title=Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 8 |pages= 4233–8 |year= 2000 |pmid= 10760291 |doi=
*cite journal | author=Xu J, Paquet M, Lau AG, "et al." |title=beta 1-adrenergic receptor association with the synaptic scaffolding protein membrane-associated guanylate kinase inverted-2 (MAGI-2). Differential regulation of receptor internalization by MAGI-2 and PSD-95. |journal=J. Biol. Chem. |volume=276 |issue= 44 |pages= 41310–7 |year= 2001 |pmid= 11526121 |doi= 10.1074/jbc.M107480200
*cite journal | author=Vazquez F, Grossman SR, Takahashi Y, "et al." |title=Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex. |journal=J. Biol. Chem. |volume=276 |issue= 52 |pages= 48627–30 |year= 2002 |pmid= 11707428 |doi= 10.1074/jbc.C100556200
*cite journal | author=Nishimura W, Yao I, Iida J, "et al." |title=Interaction of synaptic scaffolding molecule and Beta -catenin. |journal=J. Neurosci. |volume=22 |issue= 3 |pages= 757–65 |year= 2002 |pmid= 11826105 |doi=
*cite journal | author=Nakayama M, Kikuno R, Ohara O |title=Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. |journal=Genome Res. |volume=12 |issue= 11 |pages= 1773–84 |year= 2003 |pmid= 12421765 |doi= 10.1101/gr.406902
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yap CC, Muto Y, Kishida H, "et al." |title=PKC regulates the delta2 glutamate receptor interaction with S-SCAM/MAGI-2 protein. |journal=Biochem. Biophys. Res. Commun. |volume=301 |issue= 4 |pages= 1122–8 |year= 2003 |pmid= 12589829 |doi=
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Evgrafov OV, Mersiyanova I, Irobi J, "et al." |title=Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. |journal=Nat. Genet. |volume=36 |issue= 6 |pages= 602–6 |year= 2004 |pmid= 15122254 |doi= 10.1038/ng1354
*cite journal | author=Franklin JL, Yoshiura K, Dempsey PJ, "et al." |title=Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein. |journal=Exp. Cell Res. |volume=303 |issue= 2 |pages= 457–70 |year= 2005 |pmid= 15652357 |doi= 10.1016/j.yexcr.2004.10.007
*cite journal | author=Hu Y, Li Z, Guo L, "et al." |title=MAGI-2 Inhibits cell migration and proliferation via PTEN in human hepatocarcinoma cells. |journal=Arch. Biochem. Biophys. |volume=467 |issue= 1 |pages= 1–9 |year= 2007 |pmid= 17880912 |doi= 10.1016/j.abb.2007.07.027

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