APOL1

Apolipoprotein L, 1, also known as APOL1, is a human gene.cite web | title = Entrez Gene: APOL1 apolipoprotein L, 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8542| accessdate = ]

PBB_Summary
section_title =
summary_text = Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. The protein encoded by this gene is a secreted high density lipoprotein which binds to apolipoprotein A-I. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Two transcript variants encoding two different isoforms have been found for this gene.cite web | title = Entrez Gene: APOL1 apolipoprotein L, 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8542| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Duchateau PN, Pullinger CR, Orellana RE, "et al." |title=Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L. |journal=J. Biol. Chem. |volume=272 |issue= 41 |pages= 25576–82 |year= 1997 |pmid= 9325276 |doi=
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Duchateau PN, Movsesyan I, Yamashita S, "et al." |title=Plasma apolipoprotein L concentrations correlate with plasma triglycerides and cholesterol levels in normolipidemic, hyperlipidemic, and diabetic subjects. |journal=J. Lipid Res. |volume=41 |issue= 8 |pages= 1231–6 |year= 2000 |pmid= 10946010 |doi=
*cite journal | author=Duchateau PN, Pullinger CR, Cho MH, "et al." |title=Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. |journal=J. Lipid Res. |volume=42 |issue= 4 |pages= 620–30 |year= 2001 |pmid= 11290834 |doi=
*cite journal | author=Page NM, Butlin DJ, Lomthaisong K, Lowry PJ |title=The human apolipoprotein L gene cluster: identification, classification, and sites of distribution. |journal=Genomics |volume=74 |issue= 1 |pages= 71–8 |year= 2001 |pmid= 11374903 |doi= 10.1006/geno.2001.6534
*cite journal | author=Monajemi H, Fontijn RD, Pannekoek H, Horrevoets AJ |title=The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. |journal=Genomics |volume=79 |issue= 4 |pages= 539–46 |year= 2002 |pmid= 11944986 |doi= 10.1006/geno.2002.6729
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Vanhamme L, Paturiaux-Hanocq F, Poelvoorde P, "et al." |title=Apolipoprotein L-I is the trypanosome lytic factor of human serum. |journal=Nature |volume=422 |issue= 6927 |pages= 83–7 |year= 2003 |pmid= 12621437 |doi= 10.1038/nature01461
*cite journal | author=Kang MK, Kameta A, Shin KH, "et al." |title=Senescence-associated genes in normal human oral keratinocytes. |journal=Exp. Cell Res. |volume=287 |issue= 2 |pages= 272–81 |year= 2003 |pmid= 12837283 |doi=
*cite journal | author=Anderson NL, Polanski M, Pieper R, "et al." |title=The human plasma proteome: a nonredundant list developed by combination of four separate sources. |journal=Mol. Cell Proteomics |volume=3 |issue= 4 |pages= 311–26 |year= 2004 |pmid= 14718574 |doi= 10.1074/mcp.M300127-MCP200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Lugli EB, Pouliot M, Portela Mdel P, "et al." |title=Characterization of primate trypanosome lytic factors. |journal=Mol. Biochem. Parasitol. |volume=138 |issue= 1 |pages= 9–20 |year= 2005 |pmid= 15500911 |doi= 10.1016/j.molbiopara.2004.07.004
*cite journal | author=Albert TS, Duchateau PN, Deeb SS, "et al." |title=Apolipoprotein L-I is positively associated with hyperglycemia and plasma triglycerides in CAD patients with low HDL. |journal=J. Lipid Res. |volume=46 |issue= 3 |pages= 469–74 |year= 2005 |pmid= 15604524 |doi= 10.1194/jlr.M400304-JLR200
*cite journal | author=Pérez-Morga D, Vanhollebeke B, Paturiaux-Hanocq F, "et al." |title=Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. |journal=Science |volume=309 |issue= 5733 |pages= 469–72 |year= 2005 |pmid= 16020735 |doi= 10.1126/science.1114566
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Liu T, Qian WJ, Gritsenko MA, "et al." |title=Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. |journal=J. Proteome Res. |volume=4 |issue= 6 |pages= 2070–80 |year= 2006 |pmid= 16335952 |doi= 10.1021/pr0502065
*cite journal | author=Vanhollebeke B, Nielsen MJ, Watanabe Y, "et al." |title=Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 10 |pages= 4118–23 |year= 2007 |pmid= 17360487 |doi= 10.1073/pnas.0609902104

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