GJA7

GJA7

Gap junction protein, alpha 7, 45kDa, also known as GJA7, is a human gene.

PBB_Summary
section_title =
summary_text = This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.cite web | title = Entrez Gene: GJA7 gap junction protein, alpha 7, 45kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10052| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kanter HL, Saffitz JE, Beyer EC |title=Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45. |journal=J. Mol. Cell. Cardiol. |volume=26 |issue= 7 |pages= 861–8 |year= 1994 |pmid= 7966354 |doi= 10.1006/jmcc.1994.1103
*cite journal | author=Kilarski WM, Dupont E, Coppen S, "et al." |title=Identification of two further gap-junctional proteins, connexin40 and connexin45, in human myometrial smooth muscle cells at term. |journal=Eur. J. Cell Biol. |volume=75 |issue= 1 |pages= 1–8 |year= 1998 |pmid= 9523149 |doi=
*cite journal | author=Vozzi C, Dupont E, Coppen SR, "et al." |title=Chamber-related differences in connexin expression in the human heart. |journal=J. Mol. Cell. Cardiol. |volume=31 |issue= 5 |pages= 991–1003 |year= 1999 |pmid= 10336839 |doi= 10.1006/jmcc.1999.0937
*cite journal | author=Chanson M, Scerri I, Suter S |title=Defective regulation of gap junctional coupling in cystic fibrosis pancreatic duct cells. |journal=J. Clin. Invest. |volume=103 |issue= 12 |pages= 1677–84 |year= 1999 |pmid= 10377174 |doi=10.1172/JCI5645
*cite journal | author=Kausalya PJ, Reichert M, Hunziker W |title=Connexin45 directly binds to ZO-1 and localizes to the tight junction region in epithelial MDCK cells. |journal=FEBS Lett. |volume=505 |issue= 1 |pages= 92–6 |year= 2001 |pmid= 11557048 |doi=10.1016/S0014-5793(01)02786-7
*cite journal | author=Laing JG, Manley-Markowski RN, Koval M, "et al." |title=Connexin45 interacts with zonula occludens-1 in osteoblastic cells. |journal=Cell Commun. Adhes. |volume=8 |issue= 4-6 |pages= 209–12 |year= 2003 |pmid= 12064590 |doi=10.3109/15419060109080725
*cite journal | author=Kaba RA, Coppen SR, Dupont E, "et al." |title=Comparison of connexin 43, 40 and 45 expression patterns in the developing human and mouse hearts. |journal=Cell Commun. Adhes. |volume=8 |issue= 4-6 |pages= 339–43 |year= 2003 |pmid= 12064615 |doi=10.3109/15419060109080750
*cite journal | author=Xiang Q, Fan SQ, Li J, "et al." |title= [Expression of connexin43 and connexin45 in nasopharyngeal carcinoma] |journal=Ai Zheng |volume=21 |issue= 6 |pages= 593–6 |year= 2003 |pmid= 12452056 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tsai MY, Lan KC, Huang KE, "et al." |title=Significance of mRNA levels of connexin37, connexin43, and connexin45 in luteinized granulosa cells of controlled hyperstimulated follicles. |journal=Fertil. Steril. |volume=80 |issue= 6 |pages= 1437–43 |year= 2004 |pmid= 14667880 |doi=10.1016/j.fertnstert.2003.05.015
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Valiunas V, Doronin S, Valiuniene L, "et al." |title=Human mesenchymal stem cells make cardiac connexins and form functional gap junctions. |journal=J. Physiol. (Lond.) |volume=555 |issue= Pt 3 |pages= 617–26 |year= 2004 |pmid= 14766937 |doi= 10.1113/jphysiol.2003.058719
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Laing JG, Koval M, Steinberg TH |title=Association with ZO-1 correlates with plasma membrane partitioning in truncated connexin45 mutants. |journal=J. Membr. Biol. |volume=207 |issue= 1 |pages= 45–53 |year= 2007 |pmid= 16463142 |doi= 10.1007/s00232-005-0803-2
*cite journal | author=Rackauskas M, Kreuzberg MM, Pranevicius M, "et al." |title=Gating properties of heterotypic gap junction channels formed of connexins 40, 43, and 45. |journal=Biophys. J. |volume=92 |issue= 6 |pages= 1952–65 |year= 2007 |pmid= 17189315 |doi= 10.1529/biophysj.106.099358
*cite journal | author=Kotsias BA, Salim M, Peracchia LL, Peracchia C |title=Interplay between cystic fibrosis transmembrane regulator and gap junction channels made of connexins 45, 40, 32 and 50 expressed in oocytes. |journal=J. Membr. Biol. |volume=214 |issue= 1 |pages= 1–8 |year= 2007 |pmid= 17546509 |doi= 10.1007/s00232-006-0064-8

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  • Connexin — An open gap junction, composed of six identical connexin proteins. Each of these six units is a single polypeptide which passes the membrane four times (referred to as four pass transmembrane proteins). Identifiers Symbol …   Wikipedia

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