Valosin-containing protein

Valosin-containing protein

Valosin-containing protein, also known as VCP, is a human gene.cite web | title = Entrez Gene: VCP valosin-containing protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7415| accessdate = ]

PBB_Summary
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summary_text = Valosin-containing protein (VCP) is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. VCP, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.cite web | title = Entrez Gene: VCP valosin-containing protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7415| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Guinto JB, Ritson GP, Taylor JP, Forman MS |title=Valosin-containing protein and the pathogenesis of frontotemporal dementia associated with inclusion body myopathy. |journal=Acta Neuropathol. |volume=114 |issue= 1 |pages= 55–61 |year= 2007 |pmid= 17457594 |doi= 10.1007/s00401-007-0224-7
*cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=
*cite journal | author=Rabouille C, Levine TP, Peters JM, Warren G |title=An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. |journal=Cell |volume=82 |issue= 6 |pages= 905–14 |year= 1995 |pmid= 7553851 |doi=
*cite journal | author=Pleasure IT, Black MM, Keen JH |title=Valosin-containing protein, VCP, is a ubiquitous clathrin-binding protein. |journal=Nature |volume=365 |issue= 6445 |pages= 459–62 |year= 1993 |pmid= 8413590 |doi= 10.1038/365459a0
*cite journal | author=Druck T, Gu Y, Prabhala G, "et al." |title=Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP. |journal=Genomics |volume=30 |issue= 1 |pages= 94–7 |year= 1996 |pmid= 8595912 |doi= 10.1006/geno.1995.0016
*cite journal | author=Germain-Lee EL, Obie C, Valle D |title=NVL: a new member of the AAA family of ATPases localized to the nucleus. |journal=Genomics |volume=44 |issue= 1 |pages= 22–34 |year= 1997 |pmid= 9286697 |doi= 10.1006/geno.1997.4856
*cite journal | author=Hoyle J, Tan KH, Fisher EM |title=Mapping the valosin-containing protein (VCP) gene on human chromosome 9 and mouse chromosome 4, and a likely pseudogene on the mouse X chromosome. |journal=Mamm. Genome |volume=8 |issue= 10 |pages= 778–80 |year= 1997 |pmid= 9321476 |doi=
*cite journal | author=Dai RM, Chen E, Longo DL, "et al." |title=Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha. |journal=J. Biol. Chem. |volume=273 |issue= 6 |pages= 3562–73 |year= 1998 |pmid= 9452483 |doi=
*cite journal | author=Rabouille C, Kondo H, Newman R, "et al." |title=Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro. |journal=Cell |volume=92 |issue= 5 |pages= 603–10 |year= 1998 |pmid= 9506515 |doi=
*cite journal | author=Zhang SH, Liu J, Kobayashi R, Tonks NK |title=Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1. |journal=J. Biol. Chem. |volume=274 |issue= 25 |pages= 17806–12 |year= 1999 |pmid= 10364224 |doi=
*cite journal | author=Zhang H, Wang Q, Kajino K, Greene MI |title=VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells. |journal=DNA Cell Biol. |volume=19 |issue= 5 |pages= 253–63 |year= 2000 |pmid= 10855792 |doi= 10.1089/10445490050021168
*cite journal | author=Hu RM, Han ZG, Song HD, "et al." |title=Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 17 |pages= 9543–8 |year= 2000 |pmid= 10931946 |doi= 10.1073/pnas.160270997
*cite journal | author=Lavoie C, Chevet E, Roy L, "et al." |title=Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 25 |pages= 13637–42 |year= 2001 |pmid= 11087817 |doi= 10.1073/pnas.240278097
*cite journal | author=Kimonis VE, Kovach MJ, Waggoner B, "et al." |title=Clinical and molecular studies in a unique family with autosomal dominant limb-girdle muscular dystrophy and Paget disease of bone. |journal=Genet. Med. |volume=2 |issue= 4 |pages= 232–41 |year= 2001 |pmid= 11252708 |doi=
*cite journal | author=Seigneurin-Berny D, Verdel A, Curtet S, "et al." |title=Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways. |journal=Mol. Cell. Biol. |volume=21 |issue= 23 |pages= 8035–44 |year= 2001 |pmid= 11689694 |doi= 10.1128/MCB.21.23.8035-8044.2001
*cite journal | author=Yang CS, Weiner H |title=Yeast two-hybrid screening identifies binding partners of human Tom34 that have ATPase activity and form a complex with Tom34 in the cytosol. |journal=Arch. Biochem. Biophys. |volume=400 |issue= 1 |pages= 105–10 |year= 2002 |pmid= 11913976 |doi= 10.1006/abbi.2002.2778
*cite journal | author=Asai T, Tomita Y, Nakatsuka S, "et al." |title=VCP (p97) regulates NFkappaB signaling pathway, which is important for metastasis of osteosarcoma cell line. |journal=Jpn. J. Cancer Res. |volume=93 |issue= 3 |pages= 296–304 |year= 2002 |pmid= 11927012 |doi=
*cite journal | author=Kobayashi T, Tanaka K, Inoue K, Kakizuka A |title=Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells. |journal=J. Biol. Chem. |volume=277 |issue= 49 |pages= 47358–65 |year= 2003 |pmid= 12351637 |doi= 10.1074/jbc.M207783200
*cite journal | author=Uchiyama K, Jokitalo E, Kano F, "et al." |title=VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. |journal=J. Cell Biol. |volume=159 |issue= 5 |pages= 855–66 |year= 2003 |pmid= 12473691 |doi= 10.1083/jcb.200208112
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899

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