Phosphatidate cytidylyltransferase

Phosphatidate cytidylyltransferase

In enzymology, a phosphatidate cytidylyltransferase (EC number|2.7.7.41) is an enzyme that catalyzes the chemical reaction

:CTP + phosphatidate ightleftharpoons diphosphate + CDP-diacylglycerol

Thus, the two substrates of this enzyme are CTP and phosphatidate, whereas its two products are diphosphate and CDP-diacylglycerol.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:phosphatidate cytidylyltransferase. Other names in common use include CDP diglyceride pyrophosphorylase, CDP-diacylglycerol synthase, CDP-diacylglyceride synthetase, cytidine diphosphoglyceride pyrophosphorylase, phosphatidate cytidyltransferase, phosphatidic acid cytidylyltransferase, CTP:1,2-diacylglycerophosphate-cytidyl transferase, CTP-diacylglycerol synthetase, DAG synthetase, and CDP-DG. This enzyme participates in glycerophospholipid metabolism and phosphatidylinositol signaling system.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9067-83-8."

Gene Ontology (GO) codes


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