Holo-(acyl-carrier-protein) synthase
- Holo-(acyl-carrier-protein) synthase
In enzymology, a holo- [acyl-carrier-protein] synthase (EC number|2.7.8.7) is an enzyme that catalyzes the chemical reaction:
CoA- [4'-phosphopantetheine] + apo-acyl carrier protein adenosine 3',5'-bisphosphate + holo-acyl carrier protein
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CoA- [4'-phosphopantetheine] :apo- [acyl-carrier-protein] 4'-pantetheinephosphotransferase. Other names in common use include acyl carrier protein holoprotein (holo-ACP) synthetase, holo-ACP synthetase, coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine, transferase, holosynthase, acyl carrier protein synthetase, holo-ACP synthase, PPTase, AcpS, ACPS, acyl carrier protein synthase, P-pant transferase, and CoA:apo- [acyl-carrier-protein] pantetheinephosphotransferase. This enzyme participates in pantothenate and coa biosynthesis.
tructural studies
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1F7L, PDB link|1F7T, PDB link|1F80, PDB link|1FTE, PDB link|1FTF, PDB link|1FTH, PDB link|2JBZ, and PDB link|2JCA.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|37278-30-1."
Gene Ontology (GO) codes
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2010.
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