MspA porin

MspA porin
MspA
1uun opm.gif
Identifiers
Symbol MspA
Pfam PF09203
InterPro IPR015286
SCOP 1uun
OPM family 35
OPM protein 1uun

MspA porin is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel[1].

References

  1. ^ Schulz GE, Faller M, Niederweis M (2004). "The structure of a mycobacterial outer-membrane channel". Science 303 (5661): 1189–92. doi:10.1126/science.1094114. PMID 14976314.