1-alkylglycerophosphocholine O-acetyltransferase

1-alkylglycerophosphocholine O-acetyltransferase

In enzymology, a 1-alkylglycerophosphocholine O-acetyltransferase (EC number|2.3.1.67) is an enzyme that catalyzes the chemical reaction

:acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine ightleftharpoons CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine

Thus, the two substrates of this enzyme are acetyl-CoA and 1-alkyl-sn-glycero-3-phosphocholine, whereas its two products are CoA and 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase. Other names in common use include acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine, 2-O-acetyltransferase, acetyl-CoA:lyso-PAF acetyltransferase, 1-alkyl-2-lysolecithin acetyltransferase, acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase, blood platelet-activating factor acetyltransferase, lyso-GPC:acetyl CoA acetyltransferase, lyso-platelet activating factor:acetyl-CoA acetyltransferase, lysoPAF:acetyl CoA acetyltransferase, PAF acetyltransferase, platelet-activating factor acylhydrolase, platelet-activating factor-synthesizing enzyme, 1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase, and lyso-platelet-activating factor:acetyl-CoA acetyltransferase. This enzyme participates in ether lipid metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|76773-96-1."

Gene Ontology (GO) codes


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  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

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