Schistocyte

Schistocyte
Peripheral blood (MGG stain): patient with hemolytic-uremic syndrome

A schistocyte or schizocyte (from Greek schistos for "divided" or schistein for "to split", and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Schistocytes are typically irregularly shaped, jagged, and asymmetrical. A true schistocyte does not have central pallor. [1] Schistocytes are sometimes referred to as "helmet cells."

Several microangiopathic diseases, including disseminated intravascular coagulation and thrombotic microangiopathies, generate fibrin strands that sever red blood cells as they try to move past a thrombus, creating schistocytes.

Schistocytes are often seen in patients with hemolytic anemia. They are frequently a consequence of mechanical heart valve prostheses. (See artificial heart valve)

Excessive schistocytes present in blood can be a sign of microangiopathic hemolytic anemia (MAHA) where the most common cause is aortic stenosis.

References

  1. ^ Amanda Cox et al., Schistocytes: A Brief Overview. Retrieved 23 August 2008.
Lymphocytes
Smudge cell · Downey cell
Small molecules Proteins Minerals Pathogens/sepsis
Bacteremia · Viremia · Fungemia · Parasitemia · Algaemia

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Look at other dictionaries:

  • Schistocyte — Frottis sanguin montrant des schistocytes chez un patient avec un syndrome hémolytique et urémique. Les schizocytes sont des fragments de globule rouge à bords souvent déchiquetés, de forme extrêmement variable et décrits sous des noms divers.… …   Wikipédia en Français

  • schistocyte — schis·to·cyte (shĭsʹtə sīt ) n. 1. A red blood cell undergoing fragmentation. 2. A fragmented part of a red blood cell.   [Greek skhistos, split; see schist + cyte.] * * * …   Universalium

  • schistocyte — noun a red blood cell that has been fragmented by passage through damaged small vessels …   Wiktionary

  • schistocyte — A variety of poikilocyte that owes its abnormal shape to fragmentation occurring as the cell flows through damaged small vessels. SYN: schizocyte. [schisto + G. kytos, cell] * * * schis·to·cyte shis tə .sīt, skis n a hemoglobin containing… …   Medical dictionary

  • schistocyte — schis·to·cyte …   English syllables

  • schistocyte — ˈ ̷ ̷ ̷ ̷ˌsīt noun ( s) Etymology: International Scientific Vocabulary schisto + cyte 1. : a very small red blood cell 2. : a fragmenting red blood cell …   Useful english dictionary

  • helmet cell — schistocyte …   Medical dictionary

  • schizocyte — SYN: schistocyte. [schizo + G. kytos, cell] * * * schizo·cyte (skizґo sīt) schistocyte …   Medical dictionary

  • schistocit — SCHISTOCÍT s.n. Fragment al unei hematii; schizocit. [< fr. schistocyte, cf. gr. schistos – fisură, kytos – celulă]. Trimis de LauraGellner, 13.09.2007. Sursa: DN  SCHISTOCÍT s. n. schizocit. (< fr. schistocyte) Trimis de raduborza,… …   Dicționar Român

  • Thrombotic thrombocytopenic purpura — Classification and external resources Micrograph showing an advanced thrombotic microangiopathy, as may be seen in TTP. Kidney biopsy. PAS stain …   Wikipedia

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