Dodecanoyl-(acyl-carrier-protein) hydrolase

Dodecanoyl-(acyl-carrier-protein) hydrolase
dodecanoyl-[acyl-carrier-protein] hydrolase
Identifiers
EC number 3.1.2.21
CAS number 137903-37-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a dodecanoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.21) is an enzyme that catalyzes the chemical reaction

dodecanoyl-[acyl-carrier-protein] + H2O \rightleftharpoons [acyl-carrier-protein] + dodecanoate

Thus, the two substrates of this enzyme are [[dodecanoyl-[acyl-carrier-protein]]] and H2O, whereas its two products are acyl-carrier-protein and dodecanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is dodecanoyl-[acyl-carrier-protein] hydrolase. Other names in common use include lauryl-acyl-carrier-protein hydrolase, dodecanoyl-acyl-carrier-protein hydrolase, dodecyl-acyl-carrier protein hydrolase, and dodecanoyl-[acyl-carrier protein] hydrolase.

References

  • Pollard MR, Anderson L, Fan C, Hawkins DJ, Davies HM (1991). "A specific acyl-ACP thioesterase implicated in medium-chain fatty acid production in immature cotyledons of Umbellularia californica". Arch. Biochem. Biophys. 284 (2): 306–12. doi:10.1016/0003-9861(91)90300-8. PMID 1989513. 
  • Davies HM, Anderson L, Fan C, Hawkins DJ (1991). "Developmental induction, purification, and further characterization of 12:0-ACP thioesterase from immature cotyledons of Umbellularia californica". Arch. Biochem. Biophys. 290 (1): 37–45. doi:10.1016/0003-9861(91)90588-A. PMID 1898097. 
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