Inorganic diphosphatase

In enzymology, an inorganic diphosphatase (EC number|3.6.1.1) is an enzyme that catalyzes the chemical reaction

:diphosphate + H₂O $ightleftharpoons$ 2 phosphate

Thus, the two substrates of this enzyme are diphosphate and H₂O, whereas its product is phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is diphosphate phosphohydrolase. This enzyme participates in oxidative phosphorylation. It employs one cofactor, metal.

tructural studies

As of late 2007, 56 structures have been solved for this class of enzymes, with PDB accession codes PDB link|117E, PDB link|1E6A, PDB link|1E9G, PDB link|1FAJ, PDB link|1HUJ, PDB link|1HUK, PDB link|1I40, PDB link|1I6T, PDB link|1I74, PDB link|1IGP, PDB link|1INO, PDB link|1IPW, PDB link|1JFD, PDB link|1K20, PDB link|1K23, PDB link|1M38, PDB link|1MJW, PDB link|1MJX, PDB link|1MJY, PDB link|1MJZ, PDB link|1OBW, PDB link|1PYP, PDB link|1QEZ, PDB link|1SXV, PDB link|1TWL, PDB link|1UDE, PDB link|1WCF, PDB link|1WGI, PDB link|1WGJ, PDB link|1WPM, PDB link|1WPN, PDB link|1WPP, PDB link|1YGZ, PDB link|1YPP, PDB link|2AU6, PDB link|2AU7, PDB link|2AU8, PDB link|2AU9, PDB link|2AUU, PDB link|2BQX, PDB link|2BQY, PDB link|2EB0, PDB link|2EIP, PDB link|2ENX, PDB link|2HAW, PDB link|2IHP, PDB link|2IK0, PDB link|2IK1, PDB link|2IK2, PDB link|2IK4, PDB link|2IK6, PDB link|2IK7, PDB link|2IK9, PDB link|2IW4, PDB link|2PRD, and PDB link|8PRK.

References

*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|9024-82-2."

Gene Ontology (GO) codes