Myrcene synthase

Myrcene synthase
myrcene synthase
Identifiers
EC number 4.2.3.15
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a myrcene synthase (EC 4.2.3.15) is an enzyme that catalyzes the chemical reaction

geranyl diphosphate \rightleftharpoons myrcene + diphosphate

Hence, this enzyme has one substrate, geranyl diphosphate, and two products, myrcene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase (myrcene-forming). This enzyme participates in monoterpenoid biosynthesis.

References

  • Bohlmann J, Steele CL, Croteau R (1997). "Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (-)-(4S)-limonene synthase, and (-)-(1S,5S)-pinene synthase". J. Biol. Chem. 272 (35): 21784–92. doi:10.1074/jbc.272.35.21784. PMID 9268308.