Biotin-(methylcrotonoyl-CoA-carboxylase) ligase

Biotin-(methylcrotonoyl-CoA-carboxylase) ligase

In enzymology, a biotin- [methylcrotonoyl-CoA-carboxylase] ligase (EC number|6.3.4.11) is an enzyme that catalyzes the chemical reaction

:ATP + biotin + apo- [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ightleftharpoons AMP + diphosphate + [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)]

The 3 substrates of this enzyme are ATP, biotin, and ] , whereas its 3 products are AMP, diphosphate, and ] .

This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is biotin:apo- [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming). Other names in common use include biotin- [methylcrotonoyl-CoA-carboxylase] synthetase, biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase, beta-methylcrotonyl coenzyme A holocarboxylase synthetase, and holocarboxylase-synthetase. This enzyme participates in biotin metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37318-68-6."

Gene Ontology (GO) codes


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