Ribose-5-phosphate isomerase

In enzymology, a ribose-5-phosphate isomerase (EC number|5.3.1.6) is an enzyme that catalyzes the chemical reaction

:D-ribose 5-phosphate $ightleftharpoons$ D-ribulose 5-phosphate

Hence, this enzyme has one substrate, D-ribose 5-phosphate, and one product, D-ribulose 5-phosphate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-ribose-5-phosphate aldose-ketose-isomerase. Other names in common use include phosphopentosisomerase, phosphoriboisomerase, ribose phosphate isomerase, 5-phosphoribose isomerase, D-ribose 5-phosphate isomerase, and D-ribose-5-phosphate ketol-isomerase. This enzyme participates in pentose phosphate pathway and carbon fixation.

tructural studies

As of late 2007, 15 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1LK5, PDB link|1LK7, PDB link|1LKZ, PDB link|1M0S, PDB link|1NN4, PDB link|1O1X, PDB link|1O8B, PDB link|1UJ4, PDB link|1UJ5, PDB link|1UJ6, PDB link|1USL, PDB link|1XTZ, PDB link|2BES, PDB link|2BET, and PDB link|2F8M.

References

*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|9023-83-0."

Gene Ontology (GO) codes