Co-tenidone

Co-tenidone
Co-tenidone
Combination of
Atenolol Beta blocker
Chlortalidone Thiazide diuretic
Clinical data
Pregnancy cat.  ?
Legal status POM (UK)
Routes Oral
Identifiers
ATC code  ?
ChemSpider 151231 YesY
 YesY(what is this?)  (verify)

Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line because they perform less well than other drugs, and because atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes.[1]

Formulation

Two strengths of co-tenidone are currently available in the UK:

  • 50 mg atenolol and 12.5 mg chlortalidone , BAN of Co-tenidone 50/12.5
  • 100 mg atenolol and 25 mg chlortalidone , BAN of Co-tenidone 100/25

References

Footnotes

  1. ^ Sheetal Ladva (2006-06-28). "NICE and BHS launch updated hypertension guideline". National Institute for Health and Clinical Excellence. http://www.nelm.nhs.uk/Record%20Viewing/viewRecord.aspx?id=. 
v · d · eSympatholytic (and closely related) antihypertensives (C02)
Sympatholytics
(antagonize α-adrenergic
vasoconstriction)
Central
Adrenergic release inhibitors
Bethanidine • Bretylium • Debrisoquine • Guanadrel • Guanazodine • Guanethidine • Guanoclor • Guanoxan • Guanazodine • Guanoxabenz • Guanoxan
Mecamylamine • Pentolinium • Trimethaphan
Peripheral
Indirect
Tyrosine hydroxylase inhibitor
Direct
Non-selective α blocker
Other antagonists
dual (Bosentan) • selective (Ambrisentan, Sitaxentan)
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

M: VAS

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noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug(C2s+n/3/4/5/7/8/9)

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Look at other dictionaries:

  • co-tenidone — co ten·i·done (ko tenґĭ dōn) pharmacy equivalent name for a combination of atenolol, a beta adrenergic blocking agent, and chlorthalidone, a thiazide diuretic; used in the treatment of hypertension …   Medical dictionary

  • Atenolol — Systematic (IUPAC) name …   Wikipedia

  • British Approved Name — A British Approved Name (BAN) is the official non proprietary or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP). The BAN is also the official name used in many countries across the world, especially …   Wikipedia

  • Chlortalidone — Systematic (IUPAC) name (RS) 2 chloro 5 (1 hydroxy 3 oxo 2,3 dihydro 1H isoindol 1 yl)benzene 1 sulfonamide Clinical data Trade names …   Wikipedia

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