- Diethyl 2-methyl-3-oxosuccinate reductase
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diethyl 2-methyl-3-oxosuccinate reductase Identifiers EC number 1.1.1.229 CAS number 110369-21-6 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a diethyl 2-methyl-3-oxosuccinate reductase (EC 1.1.1.229) is an enzyme that catalyzes the chemical reaction
- diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+
diethyl 2-methyl-3-oxosuccinate + NADPH + H+
Thus, the two substrates of this enzyme are diethyl (2R,3R)-2-methyl-3-hydroxysuccinate and NADP+, whereas its 3 products are diethyl 2-methyl-3-oxosuccinate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase.
References
- Furuichi A, Akita H, Matsukura H, Oishi T and Horikoshi K (1987). "Purification and properties of an asymmetric reduction of diethyl 2-methyl-3-oxosuccinate in Saccharomyces fermentati". Agric. Biol. Chem. 51: 293–299.
This EC 1.1.1 enzyme-related article is a stub. You can help Wikipedia by expanding it. - diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+
