Ethamivan

Ethamivan

Drugbox
IUPAC_name = N,N-diethyl-4-hydroxy-3-methoxybenzamide



width= 200
CAS_number= 304-84-7
ATC_prefix=R07
ATC_suffix=AB04
PubChem= 9363
DrugBank=
C=12 | H=17 | N=1 | O=3
molecular_weight = 223.268
bioavailability=
metabolism =
elimination_half-life=
excretion =
pregnancy_category =
legal_status =
routes_of_administration=

Ethamivan (Etamivan, Analepticon) is a respiratory stimulant drug [Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. "Journal of Pharmacology and Experimental Therapeutics". 1975 May;193(2):657-63.] related to nikethamide. It was mainly used in the treatment of barbiturate overdose [Wheeldon PJ, Perry AW. The use of ethamivan in the treatment of barbiturate poisoning. "Canadian Medical Association Journal". 1963 Jul 6;89:20-2.] and chronic obstructive pulmonary disease, [Sproule BJ, Jans RL, Breitkreutz H, Mahon W. Effects of ethamivan in patients with chronic respiratory disease. "Canadian Medical Association Journal". 1964 Dec 5;91:1203-8.] but has now largely fallen into disuse. Some research suggests that it may have abuse potential. [Ma C, Duan H, Zhang H, Xu Y, Zhou T. Studies on analytical method for 10 drugs of abuse in urine using HPLC. (Chinese) "Yao Xue Xue Bao". 1998 Oct;33(10):764-7.]

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