Hexetidine

Hexetidine
Hexetidine
Systematic (IUPAC) name
1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat. Not to be used by pregnant women.
Legal status OTC
Routes Topical (mouthwash)
Identifiers
CAS number 141-94-6
ATC code A01AB12
PubChem CID 3607
UNII 852A84Y8LS YesY
Chemical data
Formula C21H45N3 
Mol. mass 339.602 g/mol
 YesY(what is this?)  (verify)

Hexetidine (Latin: Hexetidinum) is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.[1][2]

Hexetidine is the medicinal ingredient in Sterisol, which is labelled for the symptomatic treatment of streptococcal pharyngitis ('strep throat'), tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery.

In the UK, hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. This is produced by Mcneil, a division of Johnson & Johnson. Oraldene contains 0.1 g/100 ml of hexetidine. In some European countries, the gargle solution and mouth spray in bottles of 40 ml named Hexoral (by Mcneil) also contains 0.2% Hexetidine as its active compound. Hexetidine can also be found in the mouthwash Bactidol (by Mcneil) which is sold in many Asian countries.

Hexetidine

References

  1. ^ Kapić E, Becić F, Becić E (2002). "Hexetidine--an oral antiseptic". Med Arh 56 (1): 43–8. PMID 11917691. 
  2. ^ "Oraldene". NetDoctor.co.uk. July 8, 2004. http://www.netdoctor.co.uk/medicines/100001942.html. Retrieved 2007-04-03. 

External links