Danielle Reed

Danielle R. Reed
Residence	Pennsylvania
Citizenship	US
Fields	Biologist, Geneticist
Institutions	Monell Chemical Senses Center
Alma mater	Yale University
Doctoral advisor	Judith Rodin, Mark Friedman
Known for	Genetic variation in taste and obesity in mice and humans
Notable awards	IFF Award, 2008

Dr. Danielle R. Reed is a geneticist currently working at the Monell Chemical Senses Center in Philadelphia, Pennsylvania. She is most notable for her papers regarding genetic variation in taste and obesity in mice and humans. Her seminal studies on the genetics of bitter taste perception led to identification of a critical region of human Chromosome 5p15 whose variation correlated with a person's ability to taste the bitterness of PROP (propylthiouracil). This finding ultimately led to the discovery by Adler and co-workers (Charles Zuker) of a family of bitter taste receptors (taste receptor) located within this critical region of the chromosome. In 2008, Reed received the IFF Award For Outstanding Research On The Molecular Basis Of Taste in recognition of her contributions to the field, and delivered the IFF Lecture at the 2008 ACHemS meeting.

Background

Danielle Reed began her training as a scientist in the laboratory of Stephen Woods at the University of Washington, studying the role of hormonal signals on food intake in rodents. She did her doctoral dissertation with Judith Rodin at Yale University and Mark Friedman at the Monell Chemical Senses Center, focusing on how rodent metabolism changes in response to short term exposure to high fat diets. As a postdoctoral fellow in the laboratory of Arlen Price at the University of Pennsylvania, she learned human genetics, focusing on mapping of genes for human obesity and taste using family-based linkage methods. She established her own laboratory in 2001 at the Monell Chemical Senses Center and her research is divided between genetic mapping of obesity loci in rodent models and human genetics of taste and smell. She teaches a summer class called "A Taste of Chemistry," which is sponsored in part by The Camille and Henry Dreyfus Foundation. She collaborates with Mee-Ra Rhyu from the Korean Food Research Institute on the biology of human salt perception.

Awards

International Flavor and Fragrance Award for excellence in research, 2008

Select publications

• Mennella JA, Pepino MY, Duke FF, Reed DR. Psychophysical dissection of genotype effects on human bitter perception. Chem Senses. 2011 Jan;36(2):161-7. Epub 2010 Oct 27. PubMed PMID: 20980355; PubMed Central PMCID: PMC3020389.

• Pelchat ML, Bykowski C, Duke FF, Reed DR. Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study. Chem Senses. 2011 Jan;36(1):9-17. Epub 2010 Sep 27. PubMed PMID: 20876394; PubMed Central PMCID: PMC3002398.

• Reed DR, Zhu G, Breslin PA, Duke FF, Henders AK, Campbell MJ, Montgomery GW, Medland SE, Martin NG, Wright MJ. The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12. Hum Mol Genet. 2010 Nov 1;19(21):4278-85. Epub 2010 Jul 30. PubMed PMID: 20675712; PubMed Central PMCID: PMC2951861.

• Reed DR, Duke FF, Ellis HK, Rosazza MR, Lawler MP, Alarcon LK, Tordoff MG. Body fat distribution and organ weights of 14 common strains and a 22-strain consomic panel of rats. Physiol Behav. 2011 Jul 6;103(5):523-9. Epub 2011 Apr 15. PubMed PMID: 21504752; PubMed Central PMCID: PMC3107863.

External links

• Dr. Reed's homepage on Monell's website
• "A Taste of Chemistry" program for high school science teachers

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Name	Reed, Danielle
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