5-Methyltetrahydrofolate

5-Methyltetrahydrofolate

Chembox new
ImageFile=5-Methyltetrahydrofolate.pngImageSize=220px
IUPACName=(2"S")-2- [ [4- [(2-Amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl) methylamino] benzoyl] amino] pentanedioic acid
OtherNames=5-Methyltetrahydrofolic acid
Section1= Chembox Identifiers
CASNo=134-35-0
PubChem=9825434
SMILES=CN1C(CNC2=C1C(=O)N=C(N2)N)CNC3=CC=C(C=C3)C(=O)N [C@@H] (CCC(=O)O)C(=O)O
MeSHName=5-methyltetrahydrofolate
Section2= Chembox Properties
Formula=C20H25N7O6
MolarMass=459.46 g/mol
Appearance=
Density=
MeltingPt=
BoilingPt=
Solubility=
Section3= Chembox Hazards
MainHazards=
FlashPt=
Autoignition=

5-Methyltetrahydrofolate, or 5-methyltetrahydrofolic acid, is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine synthases).

ee also

* 5-Methyltetrahydrofolate-homocysteine methyltransferase
* S-Adenosyl methionine
* Methylenetetrahydrofolate reductase
* 5,10-Methylenetetrahydrofolate


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • methyltetrahydrofolate — noun A tetrahydrofolate with a methyl substituent, a key natural form of folate. The chief form is 5 methyltetrahydrofolate …   Wiktionary

  • 5-Methyltetrahydrofolate-homocysteine methyltransferase — 5 methyltetrahydrofolate homocysteine methyltransferase, also known as MTR, is a human gene.cite web | title = Entrez Gene: MTR 5 methyltetrahydrofolate homocysteine methyltransferase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • N5-methyltetrahydrofolate — An active one carbon derivative of tetrahydrofolate that participates in the S methylation of l homocysteine. N5 methyltetrahydrofolate:homocysteine methyltransferase methionine synthase …   Medical dictionary

  • 5-methyltetrahydrofolate — 5 meth·yl·tet·ra·hy·dro·fo·late (meth″əl tet″rə hi″dro foґlāt) a substituted, reduced derivative of folic acid, occurring as a source of methyl groups for the regeneration of methionine; it is formed by reduction… …   Medical dictionary

  • Levomefolic acid — IUPAC name (2S) 2 [ [4 [(2 Amino 5 methyl 4 oxo 1,6,7,8 tetrahydropteridin 6 yl) methylamino]benzoyl] …   Wikipedia

  • Methylenetetrahydrofolate reductase — methylene tetrahydrofolate reductase [NAD(P)H] Ribbon diagram of the active site of E. coli MTHFR. The flavin cofactor (top) is shown interacting with the bound substrate NADH.[1] …   Wikipedia

  • Methionine synthase — 5 methyltetrahydrofolate homocysteine methyltransferase PDB rendering based on 2o2k …   Wikipedia

  • Acide 5-méthyltétrahydrofolique — Structure de l acide 5 méthyltétrahydrofolique Général Synonymes ac …   Wikipédia en Français

  • Méthionine synthase — 5 méthyltétrahydrofolate homocystéine méthyltransférase ] Représentation de PDB  …   Wikipédia en Français

  • Methylenetetrahydrofolate reductase (ferredoxin) — Identifiers EC number 1.5.7.1 Databases IntEnz In …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”