Tertiary hydrogen bond

Tertiary hydrogen bond

Hydrogen bonding interaction in proteins plays a crucial role in protein folding, dynamics and function. A few percent of hydrogen bonds connect distant amino acid residues and are not involved in secondary structure stabilization. These hydrogen bonds have special role in the proteins and called tertiary hydrogen bonds cite journal|author= Bikadi Z, Demko L, Hazai E| title=Functional and structural characterization of a protein based on analysis of its hydrogen bonding network by hydrogen bonding plot| journal=Arch Biochem Biophys.|date=2007| volume=461 |issue=2 |pages=225–234 |doi=10.1016/j.abb.2007.02.020] . Tertiary hydrogen bonds can be viewed as a network enabling fast and specific (directional) communication over the whole protein.

Definition

# Hydrogen bonds that stabilize the tertiary structure of the proteins
# Off-diagonal points in the HB plot

ee also

Secondary hydrogen bond

HB Plot

Protein Structure

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Secondary hydrogen bond — IntroductionHydrogen bonding interaction in proteins plays a crucial role in protein folding, dynamics and function. The locally ordered structure, the so called secondary structure of a protein is created by hydrogen bonding within the protein… …   Wikipedia

  • Hydrogen bond — A hydrogen bond results from a dipole dipole force between an electronegative atom and a hydrogen atom bonded to nitrogen, oxygen or fluorine (thus the name hydrogen bond , which must not be confused with a covalent bond to hydrogen). The energy… …   Wikipedia

  • Hydrogen-deuterium exchange — (also called H D or H/D exchange) is a chemical reaction in which a covalently bonded hydrogen atom is replaced by a deuterium atom, or vice versa. Usually the examined protons are the amides in the backbone of a protein. The method gives… …   Wikipedia

  • Bond-dissociation energy — In chemistry, bond dissociation energy (BDE) or D0, is one measure of the bond strength in a chemical bond. It is defined as the standard enthalpy change when a bond is cleaved by homolysis,[1] with reactants and products of the homolysis… …   Wikipedia

  • Hydrogen iodide — Chembox new Name = Hydrogen iodide ImageFile = Hydrogen iodide 2D dimensions.png ImageName = Hydrogen iodide ImageFile1 = Hydrogen iodide 3D vdW.svg ImageName1 = Hydrogen iodide IUPACName = Hydrogen iodide OtherNames = hydroiodic acid Section1 =… …   Wikipedia

  • Nucleic acid tertiary structure — Example of a large catalytic RNA. The self splicing group II intron from Oceanobacillus iheyensis.[1] The tertiary structure of a nucleic acid is its precise three dimensional structure, as defined by the atomic coordinates.[2] …   Wikipedia

  • Disulfide bond — In chemistry, a disulfide bond (Br.E. disulphide bond) is a covalent bond, usually derived by the coupling of two thiol groups. The linkage is also called an SS bond or disulfide bridge. The overall connectivity is therefore R S S R. The… …   Wikipedia

  • HB plot — Knowledge of the relationship between protein’s structure and its dynamic behavior is essential for understanding protein function. The description of a protein three dimensional structure as a network of hydrogen bonding interactions (HB plot)… …   Wikipedia

  • protein — proteinaceous /proh tee nay sheuhs, tee i nay /, proteinic, proteinous, adj. /proh teen, tee in/, n. 1. Biochem. any of numerous, highly varied organic molecules constituting a large portion of the mass of every life form and necessary in the… …   Universalium

  • alcohol — /al keuh hawl , hol /, n. 1. Also called ethyl alcohol, grain alcohol, ethanol, fermentation alcohol. a colorless, limpid, volatile, flammable, water miscible liquid, C2H5OH, having an etherlike odor and pungent, burning taste, the intoxicating… …   Universalium

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”