Haplogroup DE (Y-DNA)

Haplogroup DE (Y-DNA)

In human genetics, Haplogroup DE (M1, M145, M203) is a human Y-chromosome DNA haplogroup. Haplogroup DE is the original YAP+ haplogroup [ [http://dienekes.50webs.com/blog/archives/000532.html Dienekes' Anthropology Blog] ] .

Haplogroup DE is an estimated 65,000 years old. [Karafet et al. (2008), [http://www.genome.org/cgi/content/abstract/gr.7172008v1 New Binary Polymorphisms Reshape and Increase Resolution of the Human Y-Chromosomal Haplogroup Tree] , Genome Research, DOI: 10.1101/gr.7172008]

The majority of DE male lines can be categorized as being in either haplogroup D, which likely originated in Asia, the only place where it has been foundKarafet et al. (2008), [http://www.genome.org/cgi/content/abstract/gr.7172008v1 Abstract New Binary Polymorphisms Reshape and Increase Resolution of the Human Y-Chromosomal Haplogroup Tree] , Genome Research, DOI: 10.1101/gr.7172008] , or haplogroup E, which is believed to have originated either in East AfricaCruciani et al. (2004), [http://www.familytreedna.com/pdf/hape3b.pdf Phylogeographic Analysis of Haplogroup E3b (E-M215) Y Chromosomes Reveals Multiple Migratory Events Within and Out Of Africa] , "American Journal of Human Genetics", 74: 1014-1022.] or the Near East [ [http://www.isogg.org/tree/ISOGG_HapgrpE08.html Y-DNA Haplogroup E and its Subclades - 2008] ]

The remainder are said to be in the paragroup DE* confirmed cases of which are extremely rare. In a recent study of over 8000 men worldwide including 1247 Nigerians, Haplogroup DE* was observed in only 5 Nigerian males. [Weale et al. (2003), [http://www.genetics.org/cgi/content/full/165/1/229 Rare Deep-Rooting Y Chromosome Lineages in Humans: Lessons for Phylogeography] , "Genetics, Vol. 165, 229-234]

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