MES (buffer)

MES (buffer)

Chembox new
ImageFile = MES.png ImageSize = 250px
IUPACName = 2-("N"-morpholino)ethanesulfonic acid
OtherNames =
Section1 = Chembox Identifiers
CASNo =
PubChem =
SMILES =
RTECS =
EINECS =

Section2 = Chembox Properties
Formula = C6H13NO4S
MolarMass = 195.2 g/mol
Appearance =
Density =
MeltingPt =
BoilingPt =
Solubility =

Section3 = Chembox Hazards
MainHazards =
FlashPt =
Autoignition =

MES is the common name for the compound 2-("N"-morpholino)ethanesulfonic acid. Its chemical structure contains a morpholine ring. It has a molecular weight of 195.2 and the chemical formula is C6H13NO4S. Synonyms include: 2-morpholinoethanesulfonic acid; 2-(4-morpholino)ethanesulfonic acid;, 2-(N-morpholino)ethanesulfonic acid; 2-(4-morpholino)ethanesulfonic acid; MES; MES hydrate; and morpholine-4-ethanesulfonic acid hydrate. MOPS is a similar pH buffering compound which contains a propanesulfonic moiety instead of an ethanesulfonic one.

Applications

MES is used as a buffering agent in biology and biochemistry. It was developed as one of Good's buffers in the 1960s, with pKa value of 6.15. These buffers were developed with the following criteria in mind: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pK with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range and reasonably easily synthesized. [Good, Norman E. et al., Biochemistry, 5, 467-477 (1966).] The Melting point is approx. 300 degrees C. It is soluble up to 2 M in water. It is also useful as a non-coordinating buffer in chemistry involving metal ions, as many common buffers (e.g. phosphate and acetate) readily form coordination complexes.

afety

MES is reasonably safe, but skin/eye exposure should be cleaned well with water and medical aid should be sought in the case of eye exposure/swallowing/inhalation of dust. It also emits toxic fumes upon combustion, including carbon monoxide, nitrogen oxide and sulfur oxides.

[http://www.sigmaaldrich.com/cgi-bin/hsrun/Suite7/Suite/HAHTpage/Suite.HsSigmaAdvancedSearch.formAction MSDS]

References

External links

* [http://www2.sigmaaldrich.com/suite7/Area_of_Interest/Research_Essentials/Biological_Buffers/Key_Resources/BufferCalc/SigmaAldrich_Buffer_Calculator.html?cm_mmc=wiki-_-social-_-buffer-_-MES Sigma Aldrich Buffer Calculator] - Useful tool to calculate weight, volume, or concentration from molecular weight.

ee also

*CAPSO
*CHES
*MOPS
*HEPES
*HEPPS


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • MES — The abbreviation MES may refer to: Contents 1 In the military 2 In business 3 In politics 4 In education 5 …   Wikipedia

  • Buffer solution — Acids and Bases Acid dissociation constant Acid base extraction Acid–base reaction Acid–base titration Dissociation constant Acidity function B …   Wikipedia

  • CAPS (buffer) — CAPS is the common name for N cyclohexyl 3 aminopropanesulfonic acid, a chemical used as buffering agent in biochemistry. The similar substance N cyclohexyl 2 hydroxyl3 aminopropanesulfonic acid (3 (cyclohexylamino) 2 hydroxyl 1 propanesulphonic) …   Wikipedia

  • HEPPS (buffer) — Chembox new Name = HEPPS ImageFile = HEPPS.png ImageSize = 300px ImageName = HEPPS IUPACName = 3 [4 (2 hydroxyethyl)piperazin 1 yl] propane 1 sulfonic acid OtherNames = HEPPS, EPPS Section1 = Chembox Identifiers SMILES =… …   Wikipedia

  • MOPS — Chembox new ImageFile=MOPS.png ImageSize=200px IUPACName=3 morpholinopropane 1 sulfonic acid OtherNames=3 (N morpholino)propanesulfonic acid Section1= Chembox Identifiers CASNo=1132 61 2 PubChem=70807 SMILES=C1COCCN1CCCS(=O)(=O)O Section2=… …   Wikipedia

  • The Legend of Zelda: Twilight Princess — The Legend of Zelda: Twilight Princess …   Wikipedia Español

  • High-Speed Downlink Packet Access — La tecnología HSDPA (High Speed Downlink Packet Access), también denominada 3.5G, 3G+ o turbo 3G, es la optimización de la tecnología espectral UMTS/WCDMA, incluida en las especificaciones de 3GPP release 5 y consiste en un nuevo canal compartido …   Wikipedia Español

  • New World Order — En este artículo sobre lucha libre profesional se detectaron los siguientes problemas: Necesita ser wikificado conforme a las convenciones de estilo de Wikipedia. Parece ser una traducción defectuosa. Por favor …   Wikipedia Español

  • Liste der Abkürzungen der Organischen Chemie — Diese Liste der Abkürzungen der Organischen Chemie listet die gebräuchlichsten Abkürzungen in der Organischen Chemie nach Themengebieten auf. In der Organischen Chemie werden sowohl Abkürzungen für sehr gebräuchliche Chemische Verbindungen,… …   Deutsch Wikipedia

  • Korean War — Part of the Cold War …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”