Chlorproguanil hydrochloride-dapsone-artesunate

Chlorproguanil hydrochloride-dapsone-artesunate

Chlorproguanil-dapsone-artesunate (abbreviated CDA) is a new antimalarial treatment that entered Phase III clinical trials in 2006.

It consists of chlorproguanil hydrochloride, dapsone, and artesunate. (It can also be interpreted as Lapdap+artesunate).

It is being compared against artemether-lumefantrine (Coartem) and against chlorproguanil-dapsone Lapdap. This drug is being developed in collaboration between GlaxoSmithKline, UNICEF, the World Bank, Medicines for Malaria Venture and the WHO Special Programme for Research and Training in Tropical Diseases (WHO/TDR), the Liverpool School of Tropical Medicine, and the London School of Hygiene and Tropical Medicine.[1]

References

  1. ^ Das P (2006). "Promising anti-malarial enters phase II studies.". Lancet Infect Dis 6 (9): 551. doi:10.1016/S1473-3099(06)70571-0. 

External links

Individual
agents
Other
DHFR inhibitors
(antifols)
2,4-Diaminopyrimidines (pyrimethamine)
biguanides (proguanil# • chlorproguanil)
Sulfadoxine • sulfamethoxypyrazine
Coformulation
Fansidar# (sulfadoxine/pyrimethamine)
Other
Atovaquone (as Malarone)
Tetracycline • Doxycycline#
Clindamycin
Combi-
nations
Fixed-dose (coformulated) ACTs
artemether-lumefantrine#
artesunate-amodiaquine (ASAQ)
artesunate-mefloquine (ASMQ)
dihydroartemisinin-piperaquine
artesunate-pyronaridine
Other combinations
(not co-formulated)
artesunate/SP • artesunate/mefloquine •
quinine/tetracycline • quinine/doxycycline • quinine/clindamycin
Hetero-
kont

M: PRO

ambz, excv, chrm (strc)

ambz, excv, chrm

ambz, excv, chrm

Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Chlorproguanil — IUPAC name 1 [Amino (3,4 dichloroanilino)methylidene] 2 propan 2 ylguanidine …   Wikipedia

  • CDA — may stand for:Associations and Businesses*Canadian Dental Association, an association of dentists in Canada *Canadian Dinghy Association *Caran d Ache, a famous Swiss fine arts products company. *Child Development Associate, the CDA Credential… …   Wikipedia

  • CDA — Canadian Dental Association; Certified Dental Assistant; chenodeoxycholic acid; chlorproguanil hydrochloride, dapsone, and artesunate; ciliary dyskinesia activity; clinical document architecture; complement dependent antibody; completely… …   Medical dictionary

  • CDA — • Canadian Dental Association; • Certified Dental Assistant; • chenodeoxycholic acid; • chlorproguanil hydrochloride, dapsone, and artesunate; • ciliary dyskinesia activity; • clinical document architecture; • complementdependent antibody; •… …   Dictionary of medical acronyms & abbreviations

  • Clindamycin — Systematic (IUPAC) name methyl 7 chloro 6,7 …   Wikipedia

  • Malaria prophylaxis — is a preventative treatment of malaria. Most adults from endemic areas have a degree of long term infection, which tends to recur, and also possess partial immunity (resistance); the resistance reduces with time, and such adults may become… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”