Methscopolamine

Methscopolamine

Systematic (IUPAC) name
(1R,2S,4R,5S,7R)-{[(2R)-3-hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane
Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a606008
Pregnancy cat.	?
Legal status	?
Pharmacokinetic data
Half-life	3 - 4hr
Identifiers
CAS number	155-41-9
ATC code	None
PubChem	CID 441342
DrugBank	APRD00314
ChemSpider	21106347 Y
UNII	RTN51LK7WL Y
ChEMBL	CHEMBL376897 Y
Synonyms	Methylscopolomine
Chemical data
Formula	C18H24NO4
Mol. mass	318.388 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1 Y Key:LZCOQTDXKCNBEE-IKIFYQGPSA-N Y
Y(what is this?)  (verify)

Methscopolamine, usually provided as a bromide salt (Pamine), is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion. With the advent of proton pump inhibitors and antihistamine medications it is rarely used for this anymore. It can also be used for stomach or intestinal spasms, to reduce salivation, and to treat motion sickness. Methscopolamine is also commonly used as a drying agent, to dry up post-nasal drip, in cold,irritable bowel syndrome and allergy medications (Extendryl, AlleRx, Rescon).

Methscopolamine, a methylated derivative of scopolamine, is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine. Its mechanism of action involves blocking the muscarinic acetylcholine receptors.

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.v · Categories: Anticholinergics Epoxides Quaternary ammonium compounds Tropanes Propionates Gastrointestinal system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? Mike Gregory Chuck Lorre Look at other dictionaries: methscopolamine — meth·sco·pol·amine .meth skō päl ə .mēn, mən n an anticholinergic quaternary ammonium derivative of scopolamine that is usu. used in the form of its bromide C18H24BrNO4 for its inhibitory effect on gastric secretion and gastrointestinal motility… …   Medical dictionary methscopolamine bromide — A parasympatholytic drug similar to atropine; the methyl nitrate has the same action and uses …   Medical dictionary Pamine — Pam·ine pam .ēn trademark used for a preparation of the bromide salt of methscopolamine …   Medical dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”