Uroporphyrinogen

Uroporphyrinogen

Uroporphyrinogens are tetrapyrroles with four propionic acid groups and four acetic acid groups.

There are four forms, which vary based upon the arrangements of the groups ("P") and ("A"):
* In the "I" variety, clockwise, the order repeats four times: AP-AP-AP-AP.
* In the "III" variety, the fourth is reversed: AP-AP-AP-PA.
* The "II" and "IV" varieties can be created synthetically, but do not appear in nature.

In the synthesis of porphyrin, uroporphyrinogen III is created by the enzyme Uroporphyrinogen III synthase, and the enzyme Uroporphyrinogen III decarboxylase converts it into coproporphyrinogen III.

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Look at other dictionaries:

  • Uroporphyrinogen I — Chembox new ImageFile=Uroporphyrinogen I.png ImageSize=200px IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=1867 62 5 PubChem=440775 SMILES= Section2= Chembox Properties Formula=C40H44N4O16 MolarMass=836.795 Appearance= Density=… …   Wikipedia

  • Uroporphyrinogen III decarboxylase — Uroporphyrinogen decarboxylase, also known as UROD, is a human gene.cite web | title = Entrez Gene: UROD uroporphyrinogen decarboxylase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7389| accessdate = ]… …   Wikipedia

  • Uroporphyrinogen-III-Synthase — Vorhandene Strukturdaten …   Deutsch Wikipedia

  • Uroporphyrinogen-Decarboxylase — Oberflächenmodell im Komplex mit Coproporphyrinogen nach PDB  …   Deutsch Wikipedia

  • Uroporphyrinogen III — Chembox new ImageFile=Uroporphyrinogen III skeletal.svg ImageSize= IUPACName= OtherNames= Section1= Chembox Identifiers CASNo=1976 85 8 PubChem=1179 SMILES= MeSHName=Uroporphyrinogen+III Section2= Chembox Properties Formula=C40H44N4O16… …   Wikipedia

  • Uroporphyrinogen III synthase — protein Name = uroporphyrinogen III synthase caption = width = HGNCid = 12592 Symbol = UROS AltSymbols = EntrezGene = 7390 OMIM = 606938 RefSeq = NM 000375 UniProt = P10746 PDB = ECnumber = 4.2.1.75 Chromosome = 10 Arm = q Band = 25.2 26.3… …   Wikipedia

  • uroporphyrinogen-III synthase — uro·por·phy·rin·o·gen III syn·thase (u″ro por″fə rinґə jən sinґthās) [EC 4.2.1.75] an enzyme of the lyase class that acts concertedly with hydroxymethylbilane synthase to convert porphobilinogen to uroporphyrinogen …   Medical dictionary

  • Uroporphyrinogen decarboxylase deficiency — Lack of the enzyme uroporphyrinogen decarboxylase (UROD) which is the basic cause of porphyria cutanea tarda (PCT), the late skin form of porphyria. PCT is a genetic photosensitive (light sensitive) skin disease with onset in adult life with a… …   Medical dictionary

  • uroporphyrinogen III cosynthase — uro·por·phy·rin·o·gen III co·syn·thase (u″ro por″fə rinґə jən ko sinґthās) uroporphyrinogen III synthase …   Medical dictionary

  • uroporphyrinogen decarboxylase — uro·por·phy·rin·o·gen de·car·boxy·lase (u″ro por″fə rinґə jən de kahr bokґsə lās) [EC 4.1.1.37] an enzyme of the lyase class that catalyzes the decarboxylation of uroporphyrinogen III to coproporphyrinogen III …   Medical dictionary

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