Evans blue

Evans blue

Chembox new
ImageFile = Evans blue.png ImageSize =
IUPACName =
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Section1 = Chembox Identifiers
CASNo = 314-13-6
PubChem = 6321418
SMILES =
MeSHName = Evans+blue
Section2 = Chembox Properties
Formula = C34H24N6Na4O14S4
MolarMass = 960.809
Appearance =
Density =
MeltingPt =
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Section3 = Chembox Hazards
Solubility =
MainHazards =
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T-1824 or Evans Blue, also rendered as Evan's Blue, is an Azo Compound dye which has a very high affinity for serum albumin.

Because of this, it can be useful in physiology in estimating the proportion of body water contained in blood plasma. [GeorgiaPhysiology|7/7ch02/7ch02p17]

Evans blue is also used to assess the permeability of the blood-brain barrier to macromolecules. Because serum albumin cannot cross the barrier, normally the neural tissue remains unstained. [cite journal| title=Fluorescence imaging of blood-brain barrier disruption | author=Hawkins BT, Egleton RD | journal=Journal of Neuroscience Methods| volume=151 | issue=2 | pages=262–7 | year=2006| doi=10.1016/j.jneumeth.2005.08.006]

It was named after Herbert McLean Evans, an American chemist.

ee also

* Azo compound

References

External links

*


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