Thrombin-activatable fibrinolysis inhibitor
- Thrombin-activatable fibrinolysis inhibitor
protein
Name = carboxypeptidase B2
caption =
width =
HGNCid = 2300
Symbol = CPB2
AltSymbols =
EntrezGene = 1361
OMIM = 603101
RefSeq = NM_001872
UniProt = Q96IY4
PDB =
ECnumber =
Chromosome = 13
Arm = q
Band = 14.11
LocusSupplementaryData =
Thrombin-activatable fibrinolysis inhibitor (TAFI), also known as plasma carboxypeptidase B2 is a recently described plasma zymogen that, when exposed to the thrombin-thrombomodulin complex, is converted by proteolysis at Arg92 to a basic carboxypeptidase (TAFIa or activated TAFI) that inhibits fibrinolysis.
TAFI is produced by the liver.
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