AEBSF

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IUPACName = 4-(2-Aminoethyl)benzenesulfonyl fluoride
OtherNames = Pefabloc
Section1 = Chembox Identifiers
CASNo = 34284-75-8
PubChem = 1701
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MeSHName = AEBSF
Section2 = Chembox Properties
Formula = C₈H₁₀FNO₂S
MolarMass = 203.235 g/mol
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Section3 = Chembox Hazards
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AEBSF or 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride is a water soluble, irreversible serine protease inhibitor with a molecular weight of 239.5 Da. It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. The specificity is similar to the inhibitor PMSF, nevertheless AEBSF is more stable at low pH values. Typical usage is 0.1 - 1.0 mM.