Bromhexine

Drugbox
IUPAC_name = 2,4-dibromo-6-{ [cyclohexyl(methyl)amino] methyl}aniline

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CAS_number=
ChemSpiderID = 2348
ATC_prefix=R05
ATC_suffix=CB02
ATC_supplemental=
PubChem=2442
DrugBank=
C=14 | H=20 | Br=2 | N=2
molecular_weight = 376.13
bioavailability=
metabolism =
elimination_half-life=
excretion =
pregnancy_category = A (Aus)
legal_status =
routes_of_administration=

Bromhexine is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.

Function

Bromhexine supports the body's own natural mechanisms for clearing mucus from the respiratory tract.

It is secretolytic: that is, it increases the production of serous mucus in the respiratory tract and makes the phlegm thinner and less sticky. This contributes to a secretomotoric effect: it helps the cilia - tiny hairs that line the respiratory tract - to transport the phlegm out of the lungs. For this reason it is often added to some antitussive (cough) syrups.

Sometimes it is replaced by its metabolite ambroxol, as in Mucosolvan or Mucoangin.

Brand names

* Bisolvon Forte - [http://www.bisolvon.com link International website Bisolvon.com]
* Hoesttabletten Bromhexine HCl
* Paxirasol
* Barkacin
* Vasican
* Robitussin ME