Optimal cutting temperature compound

Optimal Cutting Temperature compound (OCT) is used to embed tissue samples prior to frozen sectioning on a microtome-cryostat. This process is undertaken so as to mount slices (sections) of a sample onto slides for analysis.

Components

Composition/Data on Components: As stated on the bottle: "10.24% polyvinyl alcohol 4.26% polyethylene glycol 85.5% non-reactive ingredients"^[1]

See also

• Microtome
• Cryostat

References

1. ^ "OCT Compound, 27050, MSDS". Tedpella.com. http://www.tedpella.com/msds_html/27050msd.htm. Retrieved 2011-08-19. 

Further reading

• Turbett, Gavin; Sellner, Loryn (1997). "The use of optimal cutting temperature compound can inhibit amplification by polymerase chain reaction". Diagnostic Molecular Pathology 6 (5): 298–303. doi:10.1097/00019606-199710000-00009. PMID 9458390. 

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