NKIRAS2

NKIRAS2
NFKB inhibitor interacting Ras-like 2
Identifiers
Symbols NKIRAS2; DKFZp434N1526; KBRAS2; MGC74742; kappaB-Ras2
External IDs OMIM604497 HomoloGene9738 GeneCards: NKIRAS2 Gene
Orthologs
Species Human Mouse
Entrez 28511 71966
Ensembl ENSG00000168256 ENSMUSG00000017837
UniProt Q9NYR9 Q9CR56
RefSeq (mRNA) NM_001001349.2 NM_028024.2
RefSeq (protein) NP_001001349.1 NP_082300.1
Location (UCSC) Chr 17:
40.17 – 40.18 Mb
Chr 11:
100.48 – 100.49 Mb
PubMed search [1] [2]

NFKB inhibitor interacting Ras-like 2 is a protein that in humans is encoded by the NKIRAS2 gene.[1]

References

Further reading

  • Tago K, Funakoshi-Tago M, Sakinawa M, et al. (2010). "KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.". J. Biol. Chem. 285 (40): 30622–33. doi:10.1074/jbc.M110.117028. PMID 20639196. 
  • Fenwick C, Na SY, Voll RE, et al. (2000). "A subclass of Ras proteins that regulate the degradation of IkappaB.". Science 287 (5454): 869–73. doi:10.1126/science.287.5454.869. PMID 10657303. 
  • Dieguez-Gonzalez R, Akar S, Calaza M, et al. (2009). "Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.". Ann. Rheum. Dis. 68 (4): 579–83. doi:10.1136/ard.2007.087304. PMID 18434448. 



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