1,2-Dimethylhydrazine

1,2-Dimethylhydrazine
1,2-Dimethylhydrazine
IUPAC name
1,2-Dimethylhydrazine[1]
Other names
sym-Dimethylhydrazine[2]

N,N'-Dimethylhydrazine[2]

Hydrazomethane[2]
Identifiers
Abbreviations SDMH[2]
CAS number 540-73-8 YesY
PubChem 1322
ChemSpider 1282 YesY
UNII IX068S9745 YesY
KEGG C19176 YesY
MeSH 1,2-Dimethylhydrazine
Jmol-3D images Image 1
Properties[3]
Molecular formula C2H8N2
Molar mass 60.0983 g mol−1
Exact mass 60.068748266 g mol−1
Appearance Colourless liquid
Density 830 mg cm−3
Melting point

−9 °C, 264 K, 16 °F
Boiling point

87 °C, 360 K, 188 °F
Solubility in water Miscible
Thermochemistry
Std enthalpy of
combustion ΔcHo298		 −1.9872–−1.9788 kJ mol-1
Standard molar
entropy So298		 199.15 J K−1 mol−1
Specific heat capacity, C 171.04 J K−1 mol−1
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

1,2-Dimethylhydrazine, or symmetrical dimethylhydrazine, is one of the two isomers of dimethylhydrazine. It is a potent carcinogen that acts as a DNA alkylating agent. It is used to induce colon tumors in experimental animals.[4][1]

References

  1. ^ a b "1,2-Dimethylhydrazine - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Identification and Related Records. http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1322. Retrieved 19 October 2011. 
  2. ^ a b c d Chemical Abstracts Service: American Chemical Society, Columbus, OH, 2004; RN 540-73-8; Version 2007.3 (accessed November 4, 2011)
  3. ^ Record of 1,2-Dimethylhydrazin in the GESTIS Substance Database from the IFA
  4. ^ Cruse, JP; Lewin, MR; Ferulano, GP; Clark, CG (1978). "Co-carcinogenic effects of dietary cholesterol in experimental colon cancer". Nature 276 (5690): 822–5. doi:10.1038/276822a0. PMID 723955. 
v · d · eHydrazines
4-PTSC • Acylhydrazine • ADH • Adjudin • Agaritine • Benmoxin • Cadralazine • Carbazide • Carbazone • Carbidopa • Carbohydrazide • Daminozide • Dihydralazine • DNPH • Endralazine • Gyromitrin • HBT • Hydralazine • Hydrazide • Hydrazine • Hydrazone • IDH • Iproclozide • Iproniazid • Isocarboxazid • Isoniazid • Mebanazine • Metfendrazine • MMH • Nialamide • Octamoxin • PEH • Phenelzine • Pheniprazine • Phenoxypropazine • Phenylhydrazine • Pimagedine • Pivalylbenzhydrazine • Procarbazine • Safrazine • SDH • Semicarbazide • Semicarbazone • SDMH • Tetrafluorohydrazine • Thiosemicarbazide • Thiosemicarbazone • UDMH
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