- MicroConstants
-
MicroConstants, Inc. 
Type Private Industry Biotechnology, Contract Research Organization Founded 1998 Headquarters San Diego, California, United States Services bioanalytical method development, drug metabolism (DMPK) assays, PK analysis, immunoassay services Website www.microconstants.com MicroConstants, Inc. is a GLP-compliant Contract Research Organization (CRO) based in San Diego, California offering bioanalytical, drug metabolism, pharmacokinetics, formulation analysis and immunoassay support services to pharmaceutical and biotechnology companies[1] developing new chemical entities (NCE). The contract research services provided by MicroConstants’ bioanalytical, drug metabolism and immunoassay departments help advance their clients’ drug development programs through investigational new drug (IND) toxicology studies and clinical studies.[2]
MicroConstants’ bioanalytical services include developing and validating bioanalytical methods using high-performance liquid chromatography (HPLC) with mass spectrometric (MS/MS) detection. These methods, or assays, are then used to analyze samples (plasma, tumor, urine, fecal, etc.) from drug development studies.[3] MicroConstants uses UPLC/MS systems and laboratory equipment from Waters Corporation for method development projects.[4]
In June 2007, MicroConstants opened a second bioanalytical laboratory in Beijing, China. On March 25, 2009, MicroConstants Inc. announced that MicroConstants China Inc. had met United States Food and Drug Administration (FDA) Good Laboratory Practices (GLP) requirements.[5]
References
- ^ “Waters Expands Xevo MS Instrument Platform With Next-Generation Mass Spectrometers”, Waters Corporation, United States, May 24, 2010.
- ^ Taylor, Nick. “MicroConstants eyes east coast, NCE developing biopharm”, “Outsourcing-Pharma.com”, France, June 16, 2010.
- ^ Bonate, Peter. Beyerlein, David. Crawford, Jennifer. Roth, Stephanie. Krumbholz, Roy. Schmid, Steve. “Pharmacokinetics in Mice Implanted With Xenografted Tumors After Intravenous Administration of Tasidotin (ILX651) or Its Carboxylate Metabolite”, “The AAPS Journal”, United States, December 14, 2007.
- ^ “Waters Expands Xevo MS Instrument Platform With Next-Generation Mass Spectrometers”, Waters Corporation, United States, May 24, 2010.
- ^ “MicroConstants, A DMPK And Bioanalytical Specialty Contract Research Organization Based In San Diego, Announces Today That Its Beijing Bioanalytical Laboratory Has Met FDA GLP Requirements”, “BioSpace”, United States, March 25, 3009.
External links
Categories:- Contract research organizations
- Companies based in San Diego, California
- Companies established in 1998
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