- Meprin A
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Meprin A Identifiers EC number 3.4.24.18 CAS number 148938-24-3 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles Meprin A also known as endopeptidase-2 is an enzyme that cleaves protein and peptide substrates preferentially on carboxyl side of hydrophobic residues.[1]
Meprin A is a dimer composed of the products transcribed from the following two genes:
meprin A, alpha Identifiers Symbol MEP1A Entrez 4224 HUGO 7015 OMIM 600388 RefSeq NM_005588 UniProt Q16819 Other data EC number 3.4.24.18 Locus Chr. 6 p12-p11 meprin A, beta Identifiers Symbol MEP1B Entrez 4225 HUGO 7020 OMIM 600389 RefSeq NM_005925 UniProt Q16820 Other data EC number 3.4.24.18 Locus Chr. 18 q12.2-12.3 References
- ^ Sterchi EE, Stöcker W, Bond JS (October 2008). "Meprins, membrane-bound and secreted astacin metalloproteinases". Mol. Aspects Med. 29 (5): 309–28. doi:10.1016/j.mam.2008.08.002. PMC 2650038. PMID 18783725. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2650038.
Categories:- Genes on chromosome 6
- Genes on chromosome 18
- Biochemistry stubs
- EC 3.4.24
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