Nebacumab

Nebacumab
Nebacumab ?
Monoclonal antibody
Type Whole antibody
Source Human
Target endotoxin
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 138661-01-5 N
ATC code J06BC01
KEGG D05126 YesY
Chemical data
Formula  ?
 N(what is this?)  (verify)

Nebacumab is a human monoclonal antibody developed for the treatment of sepsis.[1] It has been withdrawn in 1993 because it failed to reduce mortality in clinical trials.[2]

References

  1. ^ Derkx, B.; Wittes, J.; McCloskey, R. (1999). "Randomized, Placebo‐Controlled Trial of HA‐1A, a Human Monoclonal Antibody to Endotoxin, in Children with Meningococcal Septic Shock". Clinical Infectious Diseases 28 (4): 770–726. doi:10.1086/515184. PMID 10825037.  edit
  2. ^ WHO: Consolidated List of Products
v · d · eMonoclonal antibodies for infectious disease and toxins
Fungal ("-fung-")
Human ("-fungu-")
Viral ("-vi(r)-")
Human ("-viru-")
Exbivirumab • Foravirumab • Libivirumab • Rafivirumab • Regavirumab • Sevirumab • Tuvirumab
Humanized ("-vizu-")
Felvizumab • Motavizumab • Palivizumab • Suvizumab
Bacterial ("-ba(c)-")
Human ("-bacu-")
Nebacumab • Panobacumab • Raxibacumab
Mouse ("-baco-")
Chimeric ("-baxi-")
Humanized ("-bazu-")
Toxin ("-tox(a)-")
Humanized ("-toxazu-")
v · d · eImmune sera and immunoglobulins (J06)
Polyclonal antibodies
Rho(D) immune globulin · Hepatitis B immune globulin · Zoster-immune globulin
Antivenom
Monoclonal antibodies
Palivizumab · Nebacumab

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)



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