Heat repeat domain

Heat repeat domain

Pfam_box
Symbol = HEAT
Name = Heat repeat


width =
caption =
Pfam = PF02985
InterPro = IPR000357
SMART=
PROSITE = PDOC50077
SCOP = 1b3u
TCDB =
OPM family =
OPM protein =
PDB = PDB2|1b3u, PDB2|1f59, PDB2|1gcj, PDB2|1ibr, PDB2|1m5n, PDB2|1o6o, PDB2|1o6p, PDB2|1qbk, PDB2|1qgr, PDB2|1u6g, PDB2|1ukl, PDB2|2bku

The HEAT repeat domain is a protein domain found in a number of cytoplasmic proteins including the four that the give rise to the acronym HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A), and the yeast PI3-kinase TOR1).cite journal | author = Andrade MA, Bork P | title = HEAT repeats in the Huntington's disease protein | journal = Nat. Genet. | volume = 11 | issue = 2 | pages = 115–6 | year = 1995 | month = October | pmid = 7550332 | doi = 10.1038/ng1095-115 | url = | issn = ] HEAT repeats form a rod-like helical structures which are involved in intracellular transport.

References


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