CLCC1

CLCC1

protein
Name=chloride channel CLIC-like 1
caption=


width=
HGNCid=29675
Symbol=CLCC1
AltSymbols=
EntrezGene=23155
OMIM=
RefSeq=NM_015127
UniProt= Q96S66
PDB=
ECnumber=
Chromosome=1
Arm=p
Band=13.3
LocusSupplementaryData=

Chloride channel CLIC-like 1 also known as CLCC1 is a human gene.cite journal | author = Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res. | volume = 5 | issue = 5 | pages = 277–86 | year = 1998 | month = October | pmid = 9872452 | doi = 10.1093/dnares/5.5.277 | url = | issn = ] cite journal | author = Nagasawa M, Kanzaki M, Iino Y, Morishita Y, Kojima I | title = Identification of a novel chloride channel expressed in the endoplasmic reticulum, golgi apparatus, and nucleus | journal = J. Biol. Chem. | volume = 276 | issue = 23 | pages = 20413–8 | year = 2001 | month = June | pmid = 11279057 | doi = 10.1074/jbc.M100366200 | url = | issn = ]

The protein encoded by this gene is a chloride channel which is related in sequence to the "S. cerevisiae" MID-1 stretch-activated channel. CLCC1 is located in the membranes of intracellular compartments including endoplasmic reticulum and the Golgi apparatus. It is highly expressed in the testis and moderately in the spleen, liver, kidney, heart, brain, and lung.

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