Microbial Symbiosis and immunity

Microbial Symbiosis and immunity

Symbiotic microorganisms, both beneficial and potentially pathogenic reside in the gastrointestinal tract of humans. Imbalances in the bacterial composition, known as dysbiosis, are thought to be a major determinant in inflammatory bowel diseases such as Crohn's disease in humans. It has long been known that intestinal microorganisms are important for the development of intestinal tissues. A recent study has demonstrated that a human symbiotic microorganism called Bacteroides fragilis protects animals from experimental colitis induced by Helicobacter hepaticus. Polysaccharide A (PSA) from this bacteria singlehandedly protects humans from the inflammatory bowel disaeses. [ [http://www.nature.com/nature/journal/v453/n7195/abs/nature07008.html A microbial symbiosis factor prevents intestinal inflammatory disease] ]

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